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Humane Society of Southeast Missouri

We envision a community where every animal has a safe and loving home.

www.semopets.org/

Cape Girardeau, MO

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Best Friends, a 501(c)(3) nonprofit organization, operates the nation's largest sanctuary for homeless animals; provides adoption, spay/neuter, and educational programs.

BEST FRIENDS REGIONAL PROGRAMS:

New York | Los Angeles | Utah | Atlanta | Houston

NO-KILL PROGRAMS:

NKLA No-Kill Los Angeles | NKUT No-Kill Utah

OTHER BEST FRIENDS SITES:

Save Them All | Best Friends Store | National Conference | Network Partners | Strut Your Mutt

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Best Friends Vet Access

As seen on National Geographic’s DogTown and the CW’s Dog Town USA. And the inspiration behind the critically acclaimed film, The Champions.

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About
Our Work
Events
The Sanctuary
Stories
Resources
- Visit the new Best Friends resource library for pet care and shelter info from animal experts.
Adopt
Ways to Give