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Humane Society of Southeast Missouri

Humane Society of Southeast Missouri (Cape Girardeau, MO) logo of cat, dog and rescue, adopt and care text

We envision a community where every animal has a safe and loving home.

Humane Society of Southeast Missouri Website

Cape Girardeau, MO 63701
United States

Help Save Them All
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We will reach no-kill in this country by 2025.

Best Friends, a 501(c)(3) nonprofit organization, operates the nation’s largest sanctuary for homeless animals; provides adoption, spay/neuter, and educational programs.

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As seen on National Geographic’s DogTown and the CW’s Dog Town USA. And the inspiration behind the critically acclaimed film, The Champions.

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Top Places to Work 2022 by the Salt Lake Tribune

As a nonprofit working every day to save homeless pets, Best Friends has been named to Fast Company’s top ten “World’s Most Innovative Companies” for using data to revolutionize how we save the lives of cats and dogs.

Fast Company Most Innovative

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